Insights on supplements, nootropics, and wellness.
14 articles matching "SIRT1".
Your skin is your largest organ and the most visible marker of aging. This guide explores the science of skin aging — from collagen loss to glycation — and which supplements, ingredients, and habits genuinely slow the process based on clinical evidence.
Mitochondria produce 95% of your body's energy, but their decline is one of the most impactful hallmarks of aging. This deep dive explores the science of mitochondrial dysfunction, why it accelerates aging, and how to support your cellular power plants.
Intermittent fasting activates many of the same longevity pathways that supplements target — autophagy, AMPK, sirtuins, and NAD+. Learn how to combine fasting with your supplement stack for maximum synergy, and which supplements to take when.
NAD+ decline is a hallmark of aging, but which NAD+ booster is best? We compare the four main precursors — NMN, NR, niacin, and tryptophan — on absorption, clinical evidence, side effects, EU availability, and cost-effectiveness.
Building a longevity supplement stack can be overwhelming. This practical guide walks you through the science-backed tiers — from foundational essentials to advanced protocols — so you can design a personalised anti-aging regimen that fits your budget and goals.
Harvard geneticist David Sinclair is one of the most influential voices in longevity science. Here's a detailed breakdown of his publicly shared supplement and lifestyle protocol, the science behind each choice, and how to adapt it for European consumers.
Quercetin is a flavonoid with dual superpowers: immune support and senolytic cell clearance. Learn the science, dosing, absorption tricks, and how it fits into a longevity stack.
The complete science-based guide to resveratrol for longevity. Learn how it activates SIRT1, what the research actually shows, the bioavailability problem, and how to dose it properly.
CoQ10 and ubiquinol both support mitochondrial energy and heart health, but they are not the same. Learn which form is better absorbed, who needs it most, and how to dose it properly.